IngestionIngestion https://www.omofmedicine.org/wp-content/uploads/2018/04/Green_Indica_.jpg 635 635 admin https://secure.gravatar.com/avatar/02783426f55984345fb7446817a2af1b?s=96&d=mm&r=g
Ingestion is an important method of administration. Anytime a patient swallows their cannabis, places it in their stomach, it is ingestion. It is metabolized differently in comparison to other methods, as it is subject to first pass liver metabolism. This means that the cannabinoids go from the gut into the liver first and then in the bloodstream. This process takes longer for the patient to get the effect, but it also stays longer in the body. Furthermore, the liver changes the chemical compounds during digestion into a smaller size of the active cannabinoid metabolites. This allows the cannabinoids to penetrate the blood-brain barrier easier which saturates the receptors located in the brain. This process can produce a more potent effect in comparison to inhalation, for example. This may explain the more intense experience patients report with ingestible forms or “edibles”.