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Key Research Findings

Physician Guide to Cannabis-Assisted Opioid Reduction. (2017)

Medical cannabis use is associated with decreased opiate medication use in a retrospective cross-sectional survey of patients with chronic pain. (2016)

• “Cannabis use associated with 64% lower opioid use in chronic pain patients.”
• “Cannabis use associated with increased quality of life in chronic pain patients.”
• “Cannabis use associated with fewer medication side effects and medications used.”

Cannabis as a substitute for opioid-based pain medication: patient self-report. (2017)

• “Cannabis can be an effective treatment for pain, greatly reduces the chance of dependence, and eliminates the risk of fatal overdose compared to opioid-based medications.”

Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence. (2015)

• “CBD has several therapeutic properties on its own that could indirectly be useful in the treatment of addiction disorders, such as its protective effect on stress vulnerability and neurotoxicity.”

Cannabidiol does not display drug abuse potential in mice behavior (2018)

• “These results show that CBD lacks activity as a drug of abuse and should stimulate the development of the basic and clinical studies needed to elucidate its potential therapeutic use for the treatment of neuropsychiatric and drug use disorders.”

Medical cannabis laws and opioid analgesic overdose mortality in the United States, 1999-2010. (2014)

•  “Medical cannabis laws are associated with significantly lower state-level opioid overdose mortality rates.”

Role of the endogenous cannabinoid system in nicotine addiction: novel insights. (2015)

Project CBD: Additional Addiction Resources.